Dr. Mathias Kuphal

At HSE, I am an expert for a microfluidics cartridge development and dry chemistry integration for point-of-care devices. I lead systems engineering projects for the automation of complex workflows analyses of nucleic acids, proteins and cells. I participate in client workshops to review novel technologies and I am involved in project proposal work. Further, I present HSE at conferences and other activities like webinars.

- Project manage the development of an assay automation software for QIAstat-dx - 2nd level support manager - Research and testing of proof-of-concept for fully integrated molecular and immunoassay diagnostic systems including microfluidics handling, dry chemistry integration and qPCR amplification. - Development of method for the separation of blood cells and blood plasma integrated in a disposable immunoassay cartridge (patented) - Experienced with the ISO 13485, IEC 62304

Senior Engineer for production processes of industry prototypes.

I designed, developed and fabricated a novel multi-electrode array of gold electrodes on a polymer substrate for a point of care device to diagnose deep vein thrombosis and I characterised the device using electrochemical impedance spectroscopy and cyclic voltammetry.

Field of Specialization: Sensors and Materials of Micro- and Nano Systems. Thesis title: A new platform for polymer-based biosensing - Fabrication technologies for an electrochemical biosensor.

• Field of study: Precision and Micro Engineering • Specialization: Biomedical Engineering • Special knowlegde: Stimulation of cells by an electric field, biocompatibility of electronic and medical products