Ommolbanin Asad Pour

• Proposed a novel combinatorial nanotechnology-assisted immunotherapy to enhance tumor-infiltrating T cell activation. • Developed strategies to block tumor-associated macrophages (TAM) with M2 phenotype, preventing T cell migration. • Focused on preventing T cell anergy and apoptosis during tumor infiltration by myeloid-derived suppressor cells (MDSCs). • Enhanced blood-brain barrier (BBB) evasion to improve therapeutic efficacy in cancer treatment.

• Conducted innovative research on combinational CSF1R/PD-L1 targeting using exosome-liposome hybrid nanoparticles. • Focused on reprogramming the immunosuppressive microenvironment in glioblastoma (GBM) and medulloblastoma (MB). • Collaborated with multidisciplinary teams at Essen University Hospital to advance cancer treatment methodologies.

• Critically evaluated submitted manuscripts for scientific rigor and methodological soundness. • Provided detailed, structured written review reports with evidence-based recommendations. • Ensured clarity of scientific presentation to enhance the quality of published research.

• Conducted quantitative localization of CARs on T cells utilizing STED super-resolution microscopy. • Analyzed the effects of stimulation on CAR distribution to enhance understanding of T cell behavior. • Collaborated with a multidisciplinary team at Göttingen Medical University to advance cancer immunotherapy research.

• Conducted in-depth research on the affinity of nanobodies against HER2 in breast cancer cells. • Collaborated with a multidisciplinary team to analyze HER2-positive and -negative cell lines. • Utilized advanced laboratory techniques to enhance understanding of cancer treatment options.

• Established and optimized laboratory protocols for molecular biology, cell biology, and epigenetic analysis. • Trained MSc-level researchers in advanced laboratory techniques and experimental design. • Contributed to research reports and manuscript preparation in the fields of reproductive genetics and cell biology.

Primer design and Real Time PCR workshops

Microsatellite analysis of genetic diversity

Microsatellite analysis of genetic diversity in Iranian chicken populations.

Dissertation: Evaluation of cell signaling of HER2-specific nanobodies and oligoclonal nanobody-targeted liposomes for breast cancer cells Remark: Signal transduction focus: PI3K/AKT, MAPK, and PLCγ1 pathway, analysis in HER2+ cancer cells; Cell cycle regulation (p27, CyclinD1)

The focus of this work was on the characterization of 16 different polymorphisms on CSN3 gene.