Dr. Otto Andersen

Industrial ecology, critical life cycle assessments, nanotoxicology, green electronics and ICT, environmental and health impacts of transport and alternative energies.

Project development for increased Europe-China cooperation in green electronics production research. Assessment of life cycle health risks of carbon nano tubes used in microelectronics.

Quality assurance and pharmaceutical regulatory affairs connected to research, development and production of iron coated mono-size polymer particles, based on the patented Ugelstad technology. The particles were active ingredients in contrast agents for magnetic resonance imaging. Establishing of quality assurance system in compliance with United States Food and Drug Administration Good Manufacturing Practices.

Characterisation of RAW 264.7 (mouse leukaemic monocyte macrophage) cell membranes for binding to a potential new cancer drug, and characterisation of solubilised receptor for the drug.

Developing and validation of analytical methods used in the analysis of pharmaceutical dosage forms (in particular, aerosol products) and pharmaceutical products. This encompassed methods for drug content, drug delivery and drug purity.

Developing new plant hormone analysis techniques and teach them to students, post-doctoral associates, and scientists visiting the Plant Growth Factors Laboratory. Computerizing the cost of hormone analysis procedures, enabling improved budgetary practices.

Finding the genetic defect responsible for cystic fibrosis. Isolated monocytes in the blood of cystic fibrosis patients and their relatives, and analysed the monocyte diaphorases (mitochondrial flavoprotein enzymes) with two-dimensional electrophoresis.

Purification and structural analysis of cord factor (trehalose 6,6' -dimycolate) derived from Mycobacterium smegmatis, an immunologically active agent important in the treatment of cancer. Utilized ion-exchange and high-performance liquid chromatography, as well as nuclear magnetic resonance spectroscopy.

Gas and liquid chromatographic, as well as immunological analysis of lipid-containing antigens from mycobacteria. Reveal specific fatty acids and polar lipids compounds or patterns of substances for use in diagnosis of mycobacteria.

Transport and Industrial Ecology. Problems and Prospects.

Lipidholdige antigener fra Mycobacterium arter. Kromatografiske og immunologiske analyser. (Lipid containing antigens from Mycobacterium species. Chromatographic and immunological analysis.)