Phillip Schiele

Assay development for in vitro characterization of monoclonal antibodies and potential combinations Experiences with tumor-targeting mAbs, immune checkpoint mAbs, small molecules, cytokines, bispecific Abs

Research project and Master thesis, Immuno-oncology - assay development and in vitro characterization of antibodies, TKIs, cytokines on immune cell functions in tumor cell co-cultures - Flow cytometry, ELISA, functional assays

Thesis at the MDC, Berlin Molecular Biology of Peptide Hormones, Prof. Dr. Michael Bader - characterization of knockout mice on RNA and protein level (in vivo and in vitro)

- Development of rationales for combinatory immunotherapies - Isolation and co-cultivation of immune cells with tumour cells - Analyzation of immune subsets (e.g. cytotoxicity assays, cell proliferation assays, methods to analyse the activation of immune cells (FACS) and cytokine release (ELISA)

Thesis at the MDC, Berlin Molecular Biology of Peptide Hormones, Prof. Dr. Michael Bader - characterization of knockout mice on RNA and protein level (in vivo and in vitro)