Tatiana Petrova

Senior research scientist Responsible for generation of high-titer stable mammalian cell lines for production of biopharmaceuticals. Optimization of the current fed-batch platform for monoclonal antibody production using shake flasks and small scales bioreactors.

Development of protocol of adaptation of adherent mammalian cell lines to growth in suspension in serum free media. Development of cell line adapted to high density. Execution of bioassays including CDC ADCC ELISA Western blot protein binding FACS to characterize cell lines and proteins of interest.

PhD in Hematology Doctoral thesis: In vitro characterisation of bone marrow stromal microenvironment of patients with aplastic anemia. Research was focused on investigating of possible mechanisms of hematopoietic failure in patients with aplastic anemia. Modulation of gene expression and adipogenic and osteogenic ability in mesenchymal stromal cells and their progeny was examined. Supervisors: Prof. N.J.Drize, MD Mykchailova E.A.

Biology