Tillmann Heinisch

• Project lead from proof of concept to pre-commercialization of disruptive enzymatic RNA synthesis for customer-installed bench-top printer to make therapeutic RNA and Crispr guide RNA cheaper, faster, with higher purity and without sharing sensitive sequence data • Helped to secure high single-digit million dollar amount as part of DNA Script's Series B and C funding rounds in 2019 and 2021 by successfully realizing key milestones within the enzymatic RNA synthesis project • Achieved bench-top RNA synthes

- Laboratories of Tom Ward and Sven Panke - Development of E. coli surface display of streptavidin-biotin-catalysts to enable in vivo new-to-nature chemistries with use as biosensors and biofactories for pharma, fragrance and food production

3D structure determination, substrate profiling and high throughput assay development for the directed evolution of a novel indol nitrating cytochrome P450 enzyme TxtE

Generation of large sets of small molecule solubility data for the development of a solubility prediction algorithm

Ph.D. with Prof. Thomas Ward (artificial metalloenzymes) and Prof. Tilman Schirmer (protein crystallography) Thesis title "Structure-Based Design of Artificial Metalloenzymes and Beyond".

Master’s thesis with Prof. Norbert Sträter (protein crystallographer), thesis title „Development of an artificial hydrogenase based on transition-metal functionalized ribonuclease A“.

I wrote a Bachelor’s thesis about the isolation and NMR-characterization of the natural products nicotine, theobromine, capsaicin and galanthamine from their natural sources. This research is published in the book "Classics in Spectroscopy, Isolation and Structure Elucidation of Natural Products" b