We are seeking a highly motivated and talented Postdoctoral Researcher (m/f/d) to join the group of Prof. Maike Sander at the Max Delbrück Center for Molecular Medicine (MDC) in Berlin. This position offers an exciting opportunity to contribute to a deeper understanding of how transcription factors shape beta-cell maturation by applying state-of-the-art multi-omic approaches in an international, vibrant, and collaborative research environment.

In a multidisciplinary effort, the Sander lab combines single-cell genomics, human stem cell models, and bioengineering approaches to investigate transcriptional and cell–cell signaling mechanisms underlying type 1 and type 2 diabetes.

As a postdoctoral researcher, you will design and implement innovative research strategies using human pluripotent stem cells to generate advanced model systems for studying beta-cell maturation and failure.

You will apply state-of-the-art molecular biology and tissue culture methods, along with next-generation sequencing (NGS) technologies, including single-cell sequencing, to interrogate transcriptional networks.

A central focus of your work will be the systematic analysis and interpretation of multi-omic datasets to uncover novel regulatory mechanisms. You will independently evaluate results, formulate hypotheses, and drive projects toward publication.

Job Description

In addition, you will:

• Preparation and documentation of research findings: You will produce comprehensive progress reports, draft scientific manuscripts for peer-reviewed journals, and design presentations for both national and international conferences.
• Presentation of scientific work: You will represent and communicate your research outcomes through talks and poster presentations at scientific meetings worldwide, thereby strengthening the international visibility of the research group.
• Contribution to methodological and technical innovation: You will develop and test novel technical approaches, optimize existing methods, and actively foster scientific discussions within the research environment.
• Engagement in collaborative projects: You will take an active role in joint research efforts, coordinate tasks with partner laboratories, and contribute to the successful implementation of interdisciplinary initiatives.

Requirements

We are looking for a researcher (m/f/d) with:

• Completed PhD: You hold a PhD in stem cell biology, molecular and cell biology, biomedical engineering, or a related discipline, with a clear and demonstrated focus on diabetes research.
• Experience with iPSC models and data analysis: Hands-on experience with induced pluripotent stem cell (iPSC) models and/or the analysis of high-throughput sequencing data is highly desirable.
• Expertise in multi-omic data analysis: Proven skills in the systematic analysis and interpretation of complex multi-omic datasets, ideally complemented by bioinformatics approaches, are welcome.
• Strong interpersonal and communication skills: You bring excellent interpersonal abilities that enable effective collaboration in a multidisciplinary and international research environment.

We offer

• international working environment with communication in English and German
• interesting career opportunities and a range of opportunities for further qualification and training
• Compatibility of family and career certified by the workandfamily audit ("berufundfamilie audit”)
• Support for "New Berliners" through the MDC Welcome & Family Office

You also benefit from:

• a remuneration in accordance with the collective agreement for the federal public service (TVöD-Bund), including additional company pension schemes
• flexible working hours and childcare support
• an idyllic green campus, which is easily accessible by bicycle, public transport or car
• free use of Nextbike from the Buch S-Bahn station to the campus
• Subsidy for the job ticket as well as discounts in the campus canteen
• On-campus health and fitness center
• additional health benefits such as flu vaccination, eye test, ergonomics advice at the workplace

Facts & figures

Salary

Remuneration will be according to the TVöD Bund, depending on the personal requirements, up to the fee group 13

Desired starting date