Masterarbeit: Advancing Organoid Magnetic Resonance Imaging with Custom Micro-MRI Technology
Masterarbeit: Advancing Organoid Magnetic Resonance Imaging with Custom Micro-MRI Technology
Masterarbeit: Advancing Organoid Magnetic Resonance Imaging with Custom Micro-MRI Technology
Masterarbeit: Advancing Organoid Magnetic Resonance Imaging with Custom Micro-MRI Technology
Max Delbrück Center for Molecular Medicine in the Helmholtz Association
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Masterarbeit: Advancing Organoid Magnetic Resonance Imaging with Custom Micro-MRI Technology
Über diesen Job
Max Delbrück Center for Molecular Medicine in the Helmholtz Association - Experimental Ultrahigh Field and Experimental and Clinical Research Center – Charité – Universitätsmedizin Berlin
Our group is continuously seeking motivated candidates to contribute to cutting-edge research in Magnetic Resonance (MR)—leveraging state-of-the-art imaging and spectroscopy techniques at ultra-high magnetic fields.
We operate one of the most advanced MR infrastructures available for research, utilizing ultra-high-field magnets up to 9.4 Tesla, paired with cryogenically cooled radiofrequency (RF) coils to maximize sensitivity and signal-to-noise ratio (SNR). This setup enables us to push the boundaries of both structural and functional MRI, including advanced diffusion-weighted imaging, novel contrast mechanisms, and high-resolution MR spectroscopy.
Our research extends beyond conventional proton (^1H) MRI. We have a strong focus on non-proton (X-nucleus) MRI, and in particular, we are pioneering new methods in fluorine (^19F) MRI. ^19F MRI offers exceptional specificity due to the negligible endogenous background signal in biological tissues, making it a powerful tool for targeted imaging. However, it also presents technical challenges due to inherently low sensitivity.
To overcome these limitations, we are developing and optimizing novel acquisition protocols, hardware solutions, and post-processing methods to enhance ^19F SNR and enable broader applications in molecular imaging, drug tracking, and metabolic studies.
If you are passionate about MR physics, imaging technology, spectroscopy, and translational biomedical research, we welcome your interest. Our projects range from method development to preclinical and translational applications and often involve interdisciplinary collaboration.
Typical candidate profiles include:
– Backgrounds in physics, biomedical engineering, electrical engineering, chemistry, or related fields
– Interest or experience in MR methods, RF systems, image reconstruction, or quantitative imaging
– Familiarity with non-proton MRI and/or molecular imaging is a plus