Post-Doc Position
Post-Doc Position
Post-Doc Position
Post-Doc Position
University Düsseldorf
Pharma, Medizintechnik
Düsseldorf
- Art der Anstellung: Vollzeit
- 41.500 € – 54.500 € (von XING geschätzt)
- Vor Ort
- Zu den Ersten gehören
Post-Doc Position
Über diesen Job
Description:
Applications are invited for a postdoctoral position at the
Institute of Neurobiology
(headed by Prof. Dr. C. R. Rose) at the Heinrich Heine University (HHU) in Duesseldorf, Germany.
The position is initially for three years with the possibility of extension (according to WissZeitVG), starting 3/2026. Salary will be in accordance with TV-L E13 (100%).
The survival and functionality of living cells depend fundamentally on maintaining ion gradients across the plasma membrane. This is particularly important for cells in the nervous system, since the charged nature of ions and their respective gradients form the basis of electrical excitability and signalling. Furthermore, ions can act as intracellular second messengers, regulating cellular processes through dynamic changes of their cytosolic concentrations. Our goal is to understand ion regulation and signalling in neurons and astrocytes of the mouse brain. One main focus lies on sodium signalling and the functional role sodium dynamics play in neurons and astrocytes as well as in the interaction of both cell types.
The position is initially for three years with the possibility of extension (according to WissZeitVG), starting 3/2026. Salary will be in accordance with TV-L E13 (100%).
The survival and functionality of living cells depend fundamentally on maintaining ion gradients across the plasma membrane. This is particularly important for cells in the nervous system, since the charged nature of ions and their respective gradients form the basis of electrical excitability and signalling. Furthermore, ions can act as intracellular second messengers, regulating cellular processes through dynamic changes of their cytosolic concentrations. Our goal is to understand ion regulation and signalling in neurons and astrocytes of the mouse brain. One main focus lies on sodium signalling and the functional role sodium dynamics play in neurons and astrocytes as well as in the interaction of both cell types.
We use dynamic, high-resolution imaging techniques, such as multi-photon laser scanning microscopy, to detect and analyse cellular ion signals in acute and cultured brain slices. Our focus is on glutamatergic synapses in the cortex, hippocampus and cerebellum of the mouse brain. These techniques are combined with electrophysiological methods, such as whole-cell patch-clamp. We use molecular tools to modify the expression of specific proteins, and we employ basic mathematical models to help us understand the function and direction of the membrane transporters and ion channels involved in ion signalling.
We are seeking a highly motivated young scientist who can work both in a team and independently. Good German and English language skills, as well as a strong work ethic, are essential. The ideal candidate will have a background in cellular imaging and/or electrophysiology. The position includes a teaching load of 4 SWS.
We offer the opportunity to participate in international conferences and provide support for further qualifications, including the option of habilitation and the opportunity to apply for third-party funding to pursue your own research interests. You will also have the opportunity to work in a new building with excellent infrastructure.
We look forward to receiving your applications. Please send your application as a single PDF file attached to an email. This should include your CV, transcripts of records and details of your research experience, a letter of motivation and a one-page summary of your PhD or most recent research project. Please also provide links to your publications and the contact details of two scientists who can provide a reference upon request.
Address and contact for questions:
Prof. Dr. Christine R. Rose
Institute of Neurobiology
