Alexandre GRIES

- Project conceptualization, investigation and supervision on repurposing kinase inhibition for medulloblastoma treatment - Development of organotypic cerebellum slice co-culture model for pathway studies, drug discovery, and drug profiling with patient derived cells - Establishement of the co-culture model in a microfluidics system to perform live imaging - Evaluation of neo-synthetized compounds on cell viability, cell death and cell invasiveness - Teacher assistant and supervision of junior scientists

- PhD preparation “Study of Histone Deacetylases (HDACs) as therapeutic targets in gastric cancer” - Investigation of the functional role of HDAC4 in gastric cancer - Drug evaluation in vitro and in vivo of HDAC inhibitors - Mission in Mexico (1 month) and continuous collaboration during my PhD preparation to evaluate neo-synthetized organometallic compounds in vitro - Supervision of undergraduate and master’s students