Andreia Marques

- Collaborated in the development and validation of reagents for gene activation in FA. - Performed RNA/DNA extractions and TaqMan assays for quantification of gene expression. - Received training in tissue and cell culture of mammalian cells, transfections and the CRISPR-Cas9 technique. - Developed a pipeline for image processing and quantification of transfection efficiency with HEK293T cells using the Cell Profiler software and an automated cell counter.

Revision and proofreading of scientific texts and publications

- General lab tasks. - Managed the storage and registry of blood samples collected for the study. - Performed genomic DNA extraction and quantification, optimisation of PCR and PCR-RFLP and electrophoresis. - Genotyped polymorphisms in genes of the GABAergic and Protein Kinase C systems and performed statistical analysis. - Presented the research work at international scientific conferences. - Participated in the supervision of undergraduate students.

Identification of novel genetic risk factors for Attention Deficit Hyperactivity Disorder (ADHD): genes of the GABAergic/Protein Kinase C systems. Achievements: - Optimised PCR/ Real-time PCR assays for allelic discrimination. - Managed big genetic databases in LINUX environment. - Developed a new pipeline for association gene-based tests. - Collaborated in in Genome-Wide Association Studies. - Integrated a multicultural team and actively participated in weekly lab meetings.