Dr. Christopher Untucht

As Lab head of the Cell Imaging Platform I develop and establish imaging based readouts for various cell-based assays in the field of neurodegenerative diseases. My spectrum reaches from high resolution confocal laser microscopy and multicolour flow cytometry to plate based high content microscopy in various plate formats up to 384wells.

Work package Co-Lead within the European IMI COMPACT consortium. The BBB work package 5 deals with macromolecular targeting across the blood brain barrier. Nanoparticular carrier systems are formulated with BBB targeting ligands to overcome the BBB. Novel targeting receptors found in proteomics and transcriptomics are characterized.

Blood-Brain Barrier model systems (ex vivo/in vitro), BBB drug targeting with biologics/ antibodies and nanoparticulate carrier systems, BBB receptor profiling; member of AbbVies BBB Initiative; Participation in the European IMI COMPACT consortium dealing with macromolecular targeting across biological barriers.

http://www.tu-braunschweig.de/ifm/abt/msteinert/groups/trypanosoma

Optimierung eines Modellsystems der Blut-Hirnschranke und dessen Anwendung in Interaktionsstudien mit afrikanischen Trypanosomen

Mikrobiologie, Zellbiologie, Physiologische Chemie