Dr. Friederike Keggenhoff

Coordinator SFB 1361 and International PhD Programme (IPP)

Cholangiocarcinoma - DNA damage response - translational medicine - CRISPR/Cas9 - siRNA - cloning - primary cell isolation - hydrodynamic tail vein injection - WB - IHC/IF • Planned and managed scientific projects, data collection and analysis of results • Established and maintained research collaborations • Organized and moderated seminars • Supervised undergraduate students • Presented and published scientific data on national and international conferences

• Assessed regulatory data for new product developments • Assisted with notifications and renewals of products in contact with national authorities • Set up of overviews and presentations to summarize regulatory information and assessments

• Implemented current quality assurance guidelines to improve work processes • Assisted in the quantification of contaminants using GC-MS / MS • performed literature research for current analyses and assessments

Impact of Poly(ADP-ribose) polymerase 1 on phenotypic and molecular features in KRAS-driven intrahepatic cholangiocarcinoma

molecular biology, food law, toxicology Masterthesis: Institut for Pathobiochemie, University Mainz "Die Proteine VAPA und VAPB als positive Modulatoren der Autophagie in primären humanen Fibroblasten und humanen Zervix-Adenokarzinom-Zellen"

molecular biology, food law, toxicology Bachelorthesis: Institute for molecular nutritional sciences "Der Einfluss des Polyphenols Resveratrol auf die Proteostase in einem transgenen Alzheimermodell des Nematoden Caenorhabditis elegans"