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Jorge Omar Yanez-Cuna

Angestellt, Associated Director / Head of R&D, Anjarium Biosciences AG
Zurich, Schweiz

Fähigkeiten und Kenntnisse

Project Management
Gene Therapy
Molecular biology
Genomics
Machine Learning
Research and Development
Competitive Intelligence
Management
Biotechnology
IP
Bioinformatics
Product Development
Technology
Data Analysis
innovative
Intellectual Property
Efficiency
Team work
DNA
Cell Biology
Gene expression
Problem Solving
Preclinical Study
preclinical
Team leadership
Leadership skills
results-oriented
Research
Communication skills
attention to detail
Customer Relationship Management
Strategic planning
Strategic management
Presentation skills
Resource Management
Teamwork
Critical thinking
Logical thinking
Conceptual thinking
strong interpersonal skills
Genetics
Sequencing
MS Office
English Language
Leadership
Biology

Werdegang

Berufserfahrung von Jorge Omar Yanez-Cuna

  • Bis heute 3 Jahre und 7 Monate, seit Nov. 2021

    Associated Director / Head of R&D

    Anjarium Biosciences AG

    Advancing company platforms, leading the competitive intelligence and strengthening intellectual property portfolios. Leading the development of synthetic DNA constructs for non-viral gene therapies and their application in the production of recombinant adeno-associated virus (rAAV), lentiviral vectors (LVV), and mRNA therapies. Spearheaded the transformation of Anjarium from a therapy-focused company into a CDMO Driving client engagement with cutting-edge technology. Building a high-performing R&D team.

  • 2 Jahre und 10 Monate, Jan. 2019 - Okt. 2021

    Principal Scientist

    Asklepios BioPharmaceutical Inc (AskBio)

    Led the preclinical work for the development of novel AAV gene therapies targeting diverse tissues (e.g. muscle, heart, liver, retina, CNS, cochlea). Led innovation in codon optimisation, promoter design, and vector development, supporting therapeutic pipelines. Collaborated with the intellectual property team in drafting patents, and conducting freedom-to-operate analysis. Contributed to two indications now in clinical trials: LGMD2I (WO2022076556) and congestive heart failure (WO2022031914).

  • 1 Jahr und 9 Monate, Apr. 2017 - Dez. 2018

    Senior Research Scientist

    Synpromics LTD

    Directed machine learning, bioinformatics, and in vivo and in vitro experiments to develop novel gene expression cassettes, enhancing the specificity and potency of AAV vectors, enabling safer and more effective gene therapy. Collaborated with the IP team in drafting patents, and conducting freedom-to-operate analysis. Engaged top-tier clients in the cell and gene therapy space, planning and managing projects under tight deadlines, while maintaining clear communication to ensure alignment and success.

  • 2 Jahre und 9 Monate, Juli 2014 - März 2017

    Postdoctoral Researcher

    Netherlands Cancer Institute (NKI)

    Developed cutting-edge genomic approaches using CRISPR/Cas9 and NGS technologies to investigate gene regulation and chromatin structure.

  • 5 Jahre, Mai 2009 - Apr. 2014

    PhD Candidate

    Research Institute of Molecular Pathology (IMP)

    Developed machine learning tools to decode how gene expression is regulated by enhancer DNA sequences. Leveraged high-throughput data (e.g. ChIP-seq, RNA-seq, and STARR-seq), to identify sequence elements critical for regulatory activity. Published several high-impact scientific papers, including one in Nature, advancing the understanding of gene regulation mechanisms and demonstrating the power of integrating machine learning and bioinformatics for breakthrough discoveries in life sciences.

Sprachen

  • Spanisch

    Muttersprache

  • Englisch

    Fließend

  • Französisch

    Gut

  • Deutsch

    Grundlagen

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