Dr. Philipp Ernst

Postdoctoral Researcher

Research Associate in the Department Hybrid Catalysis & High-Throughput-Screening. Major fields of work: Generation of bicistronic DNA constructs, development of a screening system for the directed evolution of the membrane protein FhuA, characterization of FhuA membrane proteins in black lipid membranes. Project: Chiral membranes

Research Intern and Master Thesis Candidate in the Departments Molecular Engineering and Expression & Downstream Processing. Major fields of work as Research Intern: Expression of Avian influenza vaccine candidates in N. benthamiana, downstream process develompent. Major fields of work as Master Thesis Candidate: Design and generation of Lyme disease vaccine candidates, optimization of P. pastoris for the production of recombinant proteins, initial vaccine characterizations.

Teaching Assistant in the Department of Biotechnology and Biomedical Engineering. Supervision of students in the “Practical course in Glycobiotechnology”

Research Assistant in the Department of Biotechnology and Biomedical Engineering. Major fields of work: Downstream process development, enzyme characterization. Project: Purification and characterization of the β-Galactosidase from P. furiosus

Student Trainee in the Department Quality Assurance. Major fields of work: Analysis of production plants by using classical microbiological culture techniques and rapid methods, evaluation of the corresponding results and implementation of quality assurance measures.

Research Intern and Bachelor Thesis Candidate in the Department Process Development. Major fields of work as Research Intern: Expression of Cervical cancer vaccine candidates in H. polymorpha, downstream process development, protein analysis. Major fields of work as Bachelor Thesis Candidate: Cultivation of H. polymorpha in 3 L bioreactors, downstream process development, development of a specific enzyme-based assay for product validation.

Research Intern in the Department Cell Culture Technology. Major fields of work: Cultivation of chinese hamster ovary cells in 2 L bioreactors, online/offline analytics.

Thesis: Cloning, Expression and Purification of Lyme Disease Vaccine Candidates in the methylotrophic yeast P. pastoris (1.3). Major fields of study: industrial biotechnology, protein biochemistry.

Thesis: Purification and Characterization of a soluble Variant of the Kex2 Endoproteinase from S. cerevisiae, heterologous expressed in H. polymorpha (1.3). Major fields of study: industrial biotechnology, downstream processing.

Advanced course in biology and english.