Dr. Riga Tawo

Cell Therapy & Drug Discovery. Established a portfolio of allogeneic iPSC-derived T cells, astrocytes and neurons for drug discovery and cell therapy in immuno-oncology and neuroscience. Successfully led a team of 7 scientists (4 direct reports) and various cross-functional teams. Designed, analyzed and interpreted experimental strategies and presented results at regular meetings internally and externally to partners. Headed 2 CRO project teams with Boston Biotech companies in the neuroscience space.

Advanced state-of-the-art stem cell technologies (iPSC) for disease modelling and drug development. Introduced new high-content imaging-based predictive organ toxicity platforms (kidney, endothelium & liver) in drug discovery. Expert in renal physiology, kidney development, Imaging-based High Content Screening (HCS), organoids & assay development. Managed & mentored scientists. Accomplished in presenting data internally & externally, writing scientific reports, manuscripts, IPs, risk assessments & SOPs.

Unraveling mechanism of toxicity studies of Perfluoroalkyl substances (PFAS), common food/water contaminants, cooking utensils and food packaging material using stem cell technologies. Imaging-based High Content Screening (HCS, Operetta), toxicity prediction, assay development. Established novel imaging-and flow cytometry-based drug transporter assays with the capacity to identify drug-drug-interactions (ddi). Hands-on experience with microfluidic devices. Designed cell medium (patent pending).

Head of in vivo lab (Drosophila). Focusing on protein degradation mechanisms and their impact on aging and protein aggregational diseases. Combining straight-forward mammalian cell culture (in vitro) assays with in vivo responses. Mentoring of bachelor,-master and PhD-students.

Head of in vivo lab (Drosophila). Focusing on protein degradation mechanisms and their impact on aging and protein aggregational diseases. Combining straight-forward mammalian cell culture (in vitro) assays with in vivo responses. Mentoring of bachelor,-master and PhD-students.

Erforschung von Proteinabbaumechanismen in der Zelle in Bezug auf humane Erkrankungen wie Alzheimer, Krebs und Alterung.

Entwicklungsbiologie und Genetik