Dr. Séverine Petitprez

H. Markram's group Ion channels characterisation in neurons

Optimizing the production of recombinant proteins from suspension cultures of mammalian CHO cells. Optimizing FISH protocol to detect DNA integration sites after transfection. Mycoplasma testing. Teaching and coaching of trainees.

Deciphering mechanisms underlying cardiac diseases caused by dysfunction of sodium channels. Electrophysiology (patch-clamp, drug perfusions from RT to 37°C), Immunohistochemistry, confocal microscopy, Generation of stable cell lines, Lentiviruses, Biochemistry, Management of a lab technician on a daily basis. 1 publication in CircRes

Study the regulation of cardiac and muscle sodium channels. Electrophysiology (patch-clamp, drug perfusions from RT to 37°C), Immunohistochemistry, confocal microscopy, Generation of stable cell lines, Lentiviruses, Biochemistry, Molecular biology, Teachning and coaching students and new-comers. 5 publications. Novartis prize for the best oral presentation

Set-up of a cell-culture model to reduce animal experimentation for type-2 diabetes research

Production and validation of ELISA tests kits Evaluation of dermatologic products on cell cultures

Cardiac and muscle channelopathies

Cardiac and muscle channelopathies

Purification, proteomic, immunology and microbiology techniques, Introduction to GLP and ISO, management and economy