Simon Fischer
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Fähigkeiten und Kenntnisse
Werdegang
Berufserfahrung von Simon Fischer
- Current 9 years and 8 months, since Oct 2016
Scientist
Boehringer Ingelheim Pharma GmbH & Co.KG
Wissenschaftler in der biopharmazeutischen Entwicklung
Mammalian cell line development
- Current 14 years and 3 months, since Mar 2012
Doctoral Student
International Graduate School in Molecular Medicine Ulm
Doctoral student at the international PhD programme Molecular Medicine
- Current 14 years and 6 months, since Dec 2011
Doctoral Student
Institute of Applied Biotechnology Biberach
- Enhancement of biopharmaceutical production cell systems using microRNAs. - Functional high-throughput miRNA screening in recombinant CHO cells. - Cloning of mammlian expression vectors for microRNA overexpression / inhibition. - Establishment of stable miRNA overexpressing production cells. - Functional miRNA analysis in various cancer cell lines. - Development of innovative strategies to treat in vitro tumor models. - Discovery of novel apoptosis-inducing miRNAs for cancer therapy.
- 4 months, Jan 2012 - Apr 2012
Research Scientist
Radboud University Nijmegen
- microRNA research in various mammalian cell types - Comprehensive nucleic acids and protein analysis - Establishment of a microRNA target identification assay.
- 9 months, Mar 2011 - Nov 2011
Junior Scientist
Novartis Pharma AG
- Evaluation of the novel human CAP-T cell system for transient protein expression. - Process development for high-yielding transient gene expression. - Optimization of non-viral DNA transfection technologies. - Production of recombinant antigens (including fuction proteins) and antibodies using stat-of-the-art mammalian expression hosts (CAP/CAP-T, HEK293E, HKB11, CHO-EBNA). - Scale-up of transient protein production processes up to 3L culture volume.
- Establishment of recombinant mammalian cell lines (e.g. CHO, HEK293) for functional in vitro pharmacological studies. - Development of a novel non-invasive method for studying GPCR activity based on impedance measurement. - Biochemical In vitro assay development.
Ausbildung von Simon Fischer
- 4 months, Jan 2012 - Apr 2012
Centre for Neuroscience
Radboud University of Nijmegen
Applied microRNA research in mammlian cells.
- 3 years and 4 months, Dec 2011 - Mar 2015
Pharmaceutical Biotechnology
Institute of Applied Biotechnology Biberach
Next-generation cell engineering of biopharmaceutical production systems using microRNAs.
- 1 year and 1 month, Mar 2010 - Mar 2011
Biomedical Engineering
University of Applied Sciences Albstadt-Sigmaringen
- 3 years and 5 months, Oct 2006 - Feb 2010
Pharmaceutical Biotechnology
University of Applied Sciences Biberach
Sprachen
German
C2 (Verhandlungssicher / Muttersprachlich)
English
C1 (Fließend)
French
A1-A2 (Grundkenntnisse)
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