Dr. Stefan Wietek

I am responsible for the provision of leadership and guidance to the German Ozanimod Medical Affairs Team, the implementation of all strategic and operative Ozanimod Medical Affairs initiatives and designing a comprehensive Medical Affairs program for Ozanimod for multiple sclerosis and IBD.

I support Head of Medical Affairs Neurology for largest market for injectable botulinum toxin indicated for movement disorders (incl. spasticity and dystonia) I am responsible for the medical strategy, planning and implementation, incl. development and validation of novel tools to assess patient-reported outcomes I am responsible for KOL development and training activities I provide strategic support and leadership the execution of scientific advisory boards

Continued projects as Head of GMSA (e.g., publication + communication plan) Managed new projects in neurology with focus on USA Conducted advisory boards on Alzheimer's, CIDP, dermatomyositis and immunology in USA and Canada Developed strategy and design of CTs in neurology; wrote study protocols; developed slide kits Presented Octapharma pipeline at JMF Global Summit, CA, USA

Led a team of 3 Medical/Scientific Advisors; built departmental structures Improved collaboration and information exchange with 11 local Medical Affairs organizations in N- and S-America/Europe/Australia. Managed budget for department and IITs Conducted AdBoard, Steering Committee, DMC, Investigator Meetings Presented at regulatory meetings (EMA, PEI, FDA, Health Canada) that guaranteed success of clinical development programs Published clinical studies, abstracts, posters, manuscripts

Supervised global clinical phase 1-4 studies in neurology (Alzheimer’s disease, multiple sclerosis [MS], peripheral neuropathies), immunology, haematology, and respiratory Budget management and contract research organisation (CRO) oversight Led international advisory boards and steering committee meetings Established partnerships with patient organizations and therapeutic area experts Attended neurology congresses (Alzheimer’s, MS) and had input in development of scientific promotional materials

Co-organised satellite symposia at neurology and haemophilia congresses with European marketing Managed European clinical studies (phase 3b MS trial [ISS] with partner company Biogen, haemophilia PASS) and CROs Led steering committee and investigator meetings Gave input in development of marketing strategy and materials Collaborated with European marketing team on publication plans and conferences (mainly neurology: MS)

Sales force optimisation of pharmaceutical companies.

Start-up company: Integration of vendor product data for internet catalogue, contracting of vendors, guidance of part-time employees, business development

In-house monitor, CRA: organisation of clinical trial logistics on national level

Signal transduction; immunology

Developmental neurobiology

Neurobiology, developmental biology