Varun Giri

Biostatistics in toxicological method development

• Studying autocatalytic processes for the origin of life in a Miller-Urey type experiment and analysis using chromatography and mass spectroscopy methods (GC-MS and HPLC-MS). • Studying dynamics of DNA hybridization in competition using fluorescence spectroscopy and numerical modeling.

• Designed synthetic reaction pathways and conduct feasibility assessment for bio-based production of high value-add chemicals.

• Developed data mining algorithm for extraction of reaction transformation patterns from biochemical reaction database and prediction of novel reaction pathways. • Designed synthetic reaction pathways and feasibility assessment for bio-based production of high value-add chemicals. • Performed strain optimization for incorporation of synthetic pathways using constraint based modeling. • Developed R package to compute molecule and reaction similarity for prediction of enzyme candidates.

• Developed data mining algorithm for extraction of reaction transformation patterns from biochemical reaction database and prediction of novel biochemical reaction pathways. • Developed algorithm for simultaneous multi-gene knockouts simulations.

Developed algorithms and applications for embedded systems, particularly, RF mesh networks and automated meter readers.