Vikki Semik

I managed PAVE (Paclitaxel-assisted balloon Angioplasty of Venous stenosis in haEmodialysis access), a UK multi-centre RCT, through its set-up & early recruitment phases [ISRCTN 14284759]: - obtaining Research Ethics Committee approval - obtaining NHS Permission - development of trial management documentation - site selection and set-up (national) - substantial / non-substantial amendments - safety reporting - progress reporting

I was responsible for all administrative aspects of SMILE UK (Self-Management education for adults with poorly controlled epILEpsy), a UK multi-centre RCT [ISRCTN 57937389]. - assisted with patient recruitment & retention - oversight of self-management courses - data management - source data verification - maintenance of TMF and SOPs - organisation of meetings (including minute-taking) - preparation of newsletters - managing/tracking trial documentation

- Conducted work on an independent research project - Additionally, assisted the manager of OuTSMART (Optimised TacrolimuS & MMF for HLA Antibodies after Renal Transplantation), a UK multi-centre phase IV RCT [ISRCTN 46157828] - Acted as Local Health & Safety Officer for the shared laboratory space - Managed all laboratory documentation for research work which was covered by Human Tissue Act regulations & prepared the group for audits

- Conducted work on an independent research project - Provided support to other laboratory members - Managed general laboratory processes & administration

Modules: - Fundamentals of Clinical Trials - Clinical Trials in Practice

Research title: The role of 12-lipoxygenase in non-small cell lung cancer

Final year project title: A change of inflammatory phenotype for epithelial cells: a potential therapy for asthma?