Dr. Adelia Razeto

Research project in preclinical studies, whose was financed by a grant from a private foundation. Title of the project: "The first small-molecule anti-cancer agent modulating the function of human VDAC1" The project involved the structural and biophysical characterization of the complex between hVDAC1 and the small-molecule agent. In addition, SPR experiments and fundraising for other projects, supervision of bachelor and PhD students, culturing of mouse embryonic stem cells

Research project: "Structural investigations into the catalysis coupling of Imidazoleglycerolphosphate synthase" (cell metabolism) Supervision of a PhD student

Research Project: "Structural and biochemical investigation into alkyldihydroxyacetonephosphate synthase" (perixosomal disorders) Supervision of Bachelor, Master and PhD students and technical assistants

Research project 1: "Structural studies of CylR2 from Enteroccus faecalis" (antibiotic-resistance of hospital patients) Research project 2: "Structural insights into the complex between STAT6 LXLL motif and its coactivator NCoA-1 Pas-B domain" (transcriptional regulation of the immune system) Research project 3: "Screening of expression constructs and biochemical characterization of the complex between Caspase Activated DNase (CAD) and its inhibitor ICAD " (Apoptosis)

Short term post-doc in protein crystallography in the group of Dr. V. Lamzin

PhD in protein crystallography in the group of Dr. V. Lamzin (Hamburg) and Prof. K. Wilson (York)

Introduction to protein X-ray crystallography in the group of Dr. R. Pauptit

PhD work was carried out at the EMBL outstation of Hamburg. PhD Thesis: "Structural investigation on enzymatic stereoselectivity. Two case studies: L. bulgaricus D-lactate dehydrogenase and Chymostrypsin"

Thesis project in small molecule X-ray crystallography and semi-empirical methods: "Crystalline and molecular structure of a 1,2,4-thiadiazine S,S-dioxide derivative, product of an anomalous cicloaddition" Final grade: 110 e lode/110