Angshumi Dutta

Building on my translational R&D background, I'm currently investigating post-translational modifications in mitochondrial proteins — work with direct relevance to metabolic disease, neurodegeneration, and biopharma target identification. Designing and executing cell-based assays to map mitochondrial protein regulation with high reproducibility. Standardizing molecular profiling workflows (Western Blotting) — achieving 40% uplift in experimental throughput. Managing research programs under strict SOP and d

Embedded in a clinical cartilage biology program, I built and operationalized a Human Primary Biobank from scratch — establishing infrastructure that directly supports clinical-grade translational research. Contributed to establishment of a GCP/REC-compliant Human Primary Biobank for surgical specimens; authored technical SOPs and regulatory documentation. Designed surgical tissue acquisition and transfer pipeline, increasing transfer efficiency by 30% and reducing sample degradation. Developed and validat

PhD thesis: "Role of CaMKII in modulating oxidative stress in human articular chondrocytes and osteoarthritis" — a translational program spanning clinical tissue acquisition, functional assay development, and advanced imaging. Primary strategic interface between two NHS surgical sites and university R&D team ; coordinating live tissue collection, consent workflows, and clinical sample logistics Pioneered primary cell isolation from surgical tissue and 3D ex vivo modelling; directly applicable to organoid a

Contributed to two parallel genomics programs focused on rare neurological disease — building a foundation in molecular diagnostics, NGS, and functional cell biology. Performed variant pathogenicity prediction using SIFT, PolyPhen2, and Mutation Taster across patient cohorts for a novel epilepsy gene linked to Juvenile Myoclonic Epilepsy Conducted NGS-based target gene identification in collaboration with a cross-functional team of 10+ scientists Executed Sanger sequencing, PCR, and cell immunofluorescence

During my M.Sc, I gained a grasp on a plethora of basic and advanced level courses like recombinant DNA technology, molecular biology, cell biology, physiology, genetics, immunology. In the final year, I specialized in neuroendocrinology, reproductive biology, and molecular endocrinology. I conduc

During college years, I got a clearer picture of life forms' complexities through various courses like molecular biology, cell biology, immunology, physiology, biostatistics, and genetics. My efforts and sincerity enabled me to acquire the position of a college topper; this accolade only enhanced m