Chih-Chieh Tsao

•Led cross-departmental research projects on vascular-brain interactions, advancing mechanistic understanding in neurovascular biology and cerebral ischemia. Designed and executed preclinical experiments using in vivo models, histology, immunostaining, and imaging workflows to generate high-quality, interpretable datasets. •Analyzed experimental results with scientific rigor and translated findings into clear biological insights for research planning, reporting, and publication development. •Strengthened fu

•Managed laboratory operations and optimized administrative processes, ensuring smooth workflows and timely project delivery. •Performed experiments and analyzed data, contributing to manuscript preparation and the effective presentation of research findings.

Managed neurovascular research projects with ETHZ, acting as the primary researcher, designing and conducting experiments, mentoring master’s students, and co-authored to two publications. Secured competitive Forschungskredit funding, demonstrating expertise in grant writing, project planning, and resource acquisition for independent research. Presented research findings at multiple international conferences, earning recognition through poster awards and selected talks that underscored the impact of my wo

•Managed collaborative neurovascular research projects with ETH Zurich as the primary researcher, overseeing study design, experiment execution, and data interpretation. •Applied in vivo models, microscopy, histology, and molecular biology techniques to investigate blood-brain barrier function and post-stroke mechanisms. •Mentored master’s students in experimental workflows and supported high-quality project execution within collaborative research settings. •Co-authored two peer-reviewed publications and pr

Project:Methylation level of vav1 and its role in pancreatic cancer progression. Contribution: 1.The effect of vav1 over-expression and knockdown on epithelia-mesenchymal transition in pancreatic cancer cell lines. 2.Vav1 expression in pancreatic cell lines after TGF-beta and TNF-alpha treatment. 3.K-Ras, Mucin-4, PTEN, DBA-lectin and α-amylase expression in human pancreatic cancer.

Project:Hepatitis B Virus X Protein Up regulates mTOR Signaling through IKKβ to Increase Cell Proliferation and VEGF Production in Hepatocellular Carcinoma. Contribution: 1.The effect of HBX overexpression on IKKβ/TSC1/mTOR signaling in human hepatoma Hep 3B and Hep G2 cell line by western blotting. 2. HBx-mediated upregulation of IKKβ/TSC1/mTOR signaling is associated with liver tumor genesis in HBx transgenic mice by western blotting and immunohistochemistry. Project:Expression of microRNA 106b and its ro

Project:Development of Abdominal Aortic Aneurysm in a Porcine Model 1.Establishing an abdominal aortic aneurysm model in porcine by coarctation of an infrarenal abdominal aorta segment. 2.Investigation of the pathogenesis of abdominal aortic aneurysm by H&E stain, Verhoeff’s stain and Masson’s trichrome stain.

Institute of Veterinary Physiology, UZH. Supervisor: PD Dr. O. Ogunshola Thesis: Pericyte Hypoxia-Inducible Factor-1 (HIF-1) Signaling Regulates Blood-Brain Barrier Function and Outcome Post-Stroke.

Master’s Thesis: Neuroprotective and Neuroplastic Effects of Melatonin in Aged Mice Subjected to Permanent Focal Cerebral Ischemia.