Dr. Dorota Nüß
Werdegang
Berufserfahrung von Dorota Nüß
- Bis heute 8 Jahre und 11 Monate, seit Juli 2016
Quality Assurance Manager, GMP Auditor
Novartis Technical Operations
Supplier Management & Audits Organization Audit Management Supplier Qualification Management Performance of self-inspection Management of cGMP documentation - SOP’s, Working Instructions, Validation Reports, Forms CAPA Management
Audit Management Supplier Qualification Management Performance of self-inspection audits to ensure compliance with Quality Management System procedures and cGMP regulations Management of cGMP documentation - SOP’s, Working Instructions, Testing Procedures, Batch Records, Validation Reports, Annual Product- and Annual Raw Material Reviews, CAPA Management
- 8 Jahre und 9 Monate, Jan. 2006 - Sep. 2014
Project Leader Elise-Richter-Program
University of Salzburg, Billrothstrasse 11, 5020 Salzburg, Austria
Projectmanangement Biochemical and structural investigations on clostridial pathogen-related proteases: determination of a flexible expression and purification platform for high-yield production of soluble and functional therapeutic proteins, biochemical characterization, crystallization and structure determination Structural analysis of the molecular basics of the allergenicity Teaching activities: Lectures Mentoring of technical assistants, internship-, master- and PhD- students
- 2 Jahre und 8 Monate, Mai 2003 - Dez. 2005
Post-doctoral training
Max-Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried
Establishing of cloning, expression, purification and crystallization strategy for membrane proteins, particularly members of the ADAM (a disintegrin and metalloproteinase) proteins family; cloning and expression in different systems (E. coli, Baculovirus, Drosophila and mammalian cells), screening and setup for the high-yield protein production, optimization of purification procedures, preliminary crystallization and kinetic studies of enzymes
- 4 Monate, Jan. 2003 - Apr. 2003
Scientist, Protein biochemistry & Assay Development
4SC AG, Am Klopferspitz 19, 82152 Martinsried, Germany
Setup and validation of enzyme assays, kinetic studies of enzymes, crystallization and structure determination of protein-inhibitor complexes Mentoring of technical assistants
Ausbildung von Dorota Nüß
- 3 Jahre und 3 Monate, Okt. 1999 - Dez. 2002
Molecular Biology and Biotechnology
Technical University Munich / Max-Planck Institute of Biochemistry
Structural studies of several proteins involved in photosynthesis, the regulation of cytoskeleton and a cyclase associated protein (CAP)
- 1 Jahr, Okt. 1998 - Sep. 1999
Research Assistant
Institute of Medical Chemistry, Jagiellonian University, Krakow, Poland
Expression of beta1-integrins and N-cadherin in bladder cancer and melanoma cell lines. Experince in mammalian cell culture and expertise in immunological in vitro assays including immunoprecipitation, ELISA, and FACS analysis
- 5 Jahre, Okt. 1993 - Sep. 1998
Chemistry
Institute of Chemistry, Jagiellonian University, Krakow, Poland
Sprachen
Deutsch
Fließend
Englisch
Fließend
Russisch
Gut
Polnisch
Muttersprache
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