Dr. Hyunju Oh-Strauss

Laboratory of Dr. Sankar Ghosh • Elucidated the role of NF-kappa B signaling in the development and function of regulatory T cells using various transgenic mouse strains and multiple immunological methods • Discovered how NF-kappa B controls genes differentially in conventional T and regulatory T cells by analyzing RNAseq and ChIPseq data • Oh H, Grinberg-Bleyer Y and Ghosh S et al. Immunity, 2017 Sep 19: 47:1-16 • Grinberg-Bleyer Y, Oh H, and Ghosh S et al. Cell, 2017 Sep 7:170(6):1096–1108

Laboratory of Dr. Sankar Ghosh • Elucidated the role of NF-kappa B signaling in the development and function of regulatory T cells using various transgenic mouse strains and multiple immunological methods • Discovered how NF-kappa B controls genes differentially in conventional T and regulatory T cells by analyzing RNAseq and ChIPseq data

• Thesis title: A chemical genetic approach to the study of Syk and B cell antigen receptor signaling • Developed a novel inhibitor designed to target the ATP-binding pocket of Syk protein tyrosine kinase to better elucidate the role of Syk in B cell receptor signaling