Jürgen Holzapfel

Project Manager for a investment programme („Biotest Next Level“~ € 250 million) at Biotest . This programme includes the construction of a fractionation plant , production facilities for Albumin, IgG, Fibrinogen and IgM, Quality Controll Labs. Conceptual study for a new plasma fractionation plant including purification facilities , filling and packaging, QC labs, etc. for a chinese customer Stratetic advise in the plasma business for different costumers

Responsible for all manufacturing operations in Germany as well as at cooperation partners like CAF-DCF , Kedrion , Sanquin Strategical reorganisation of manufacturing operations Enlargement of the production capacity Extension and upgrade of different maufacturing facilities; Co -Initiator of the investment program „Biotest Next Level“

Responsible for all bulk production operations in Germany Reorganisation of the department Extension and (GMP and technical)upgrade of different bulk production facilities Implementation of different new production processes and technique(IgG, basic fractionation process, Albumin, Factor VIII, Factor IX) Responsible for process transfer to different international partners

Operational and organisationel restructuring of the departments production and QC Implementation of quality assurance tools into the organisation Organisational integration of the engineering and maintance group into the production department Extension and upgrade(GMP and technical) of the production department Implementation of different new production processes and technique( Basic fractionation process, Albumin, Factor VIII, PPSB, IgG)

Establishment of new departments for Plasmaprotein derivates and QC of plasma derivates Employee selection for the departments Staff training Start up of the Production site and the QC labs Implementation of production processes and equipment Optimisation of processes Establishment of a development lab.