Dr. Kilian Zilkens

Generation of monoclonal and multiclonal antibodies using phage display. Providing highly specific non-animal derived antibodies for diagnostics. Promoting the use of animal-free products in life science research and diagnostics.

Generation cDNA-based protein fragment libraries from tissue samples. Phage display panning against patient antibody repertoires for the identification of novel tumor associated proteins. Screenings in ELISA format or via NGS. Experience in method development. Insights into project planning. Communication with clinicians and cooperation partners. Procurement of patient samples.

Antibody discovery in the department of protein engineering and antibody technologies. Generation and testing of yeast surface FAB libraries. Enrichment of antibodies with desired characteristics via high-throughput FACS in several rounds of selection.

Toxikologie, Zellbiologie, Krebsbiologie, Stammzellen, Abschlussarbeit über genetische Subtypisierung von Brustkrebs

Vertiefungen in Naturstoffchemie, Immunbiologie und Humangenetik. Abschlussarbeit über Veränderungen der Proteinmengen der Sirtuine (SirT1-7) bei kardialer Hypertrophie.