Lizeth Bodero

• Synthesis of fluorinated foldamers with potential CPP/AMP activity. • Analysis of 19F NMR and 2D NMR spectroscopy data for structure determination. • Preparation of building blocks for solid phase peptide synthesis. • Presentation of results at project meetings, participation in scientific events.

• Synthesis of isoDGR-CPP-paclitaxel conjugates as new drug delivery system. • Coordination of in vitro assays in collaboration with external partners. • Interpretation of biological results. • Contribution to lab management: control of stock of chemical products, consumables, maintenance of lab equipment. • Supervision of Master/Bachelor students during their internships at the laboratory.

• Synthesis of peptidomimetic-drug conjugates for tumor targeting. • Optimization and scale-up of the synthesis of cyclo[DKP-isoDGR] integrin ligand. • In vitro evaluation of antitumor activity of the conjugates in collaboration with biology teams. • Industrial PhD secondment: Heidelberg Pharma GmbH, Ladenburg, Germany (01/2017 – 06/2017) • Communication with the internal project team and the European network partners. • Generation of scientific output related to the project

• Preparation of material for laboratory sessions. • Support to students during the practical laboratory work.

• Topic: Synthesis of phloroglucinol derivatives with potential anti-AGE activity. • Study of structure-activity relationship (SAR). • Anti-AGE (advanced glycation products) fluorescence tests.

• Topic: Synthesis of 2,3-diarylimidazo[1,2-a]pyrazines with potential antileishmanial activity.

Topic: Evaluation of two synthetic pathways in total synthesis of cercosporamide.

• Chemical formulation and product development for textile and adhesive industry. • Quality control of raw materials.