Dr. Mira Jung

-Direct a translational research program centered on the immune-fibrotic axis and metabolic regulation in heart failure, leveraging 15+ years of R&D expertise to drive pipeline progression from early discovery to target validation -Lead cross-functional strategy for novel target discovery and validation, accelerating therapeutic candidate advancement through data-driven milestone execution and multidisciplinary collaboration

-Uncovered IL-10-driven immunometabolic signaling pathways that drive reparative macrophage polarization, improving cardiac function and reducing post-MI fibrosis. -Characterized immune-stromal dynamics—including macrophage-fibroblast interactions, phagocytosis, and matrix remodeling—via mechanistic in vivo models. -Executed LAD ligation, serial echo, and biomarker studies, integrating glycoproteomic/secretome data to identify remodeling targets.

-Patent KR 10-2011-0116730. -Dissertation: Spinasterol-glucose and synthetic derivatives attenuate inflammatory responses in keratinocytes and a DNCB-induced mouse model.