Dr. Rui Pedro Lopes

Research in the field of Biophysics and Physical Biochemistry. Main tasks included structural and dynamic studies of proteins using NMR, X-ray crystallography, calorimetry (ITC), microscale thermophoresis (MST) and differential scanning calorimetry (DSC and nanoDSF).

Organic synthesis of artificial peptides and organomatallic Ruthenium and palladium catalysts used for important hydrogenation reactions. Main competences involved synthetic chemistry, chromatography and molecular spectroscopy (NMR, Uv-Vis)

Synthesis and characterization of metal-DNA complexes using vibrational spectroscopy and NMR as main instrumental techniques

Thermodynamics, Structure and Inhibition of the Ras protein. A biophysical Approach using Nuclear Magnetic Resonance (NMR) and X-Ray crystallography as main techniques

Organic synthesis of Platinum-DNA complexes and their characterization using vibrational spectroscopy (FTIR, Raman, neutron scattering) coupled with quantum mechanic calculations (ab initio methods: DFT and Plane Wave).