Dr. Thomas Schröter

Angestellt, Medicine Properties Group Leader in Discovery Sciences, Pfizer Inc.
Groton, Vereinigte Staaten

Fähigkeiten und Kenntnisse

Drug Discovery
Toxicology
ADME
in vitro pharmacology

Werdegang

Berufserfahrung von Thomas Schröter

  • Bis heute 8 Jahre und 7 Monate, seit Dez. 2016

    Medicine Properties Group Leader in Discovery Sciences

    Pfizer Inc.

    Focus on the creation of high-quality translatable lead matter to enable and accelerate design to clinical outcome. Strategic, scientific and operational responsibility to identify, develop and implement ADME, toxicology and biopharmaceutical properties screens to enable holistic assessment of early portfolio quality, to drive chemistry design, and to set a clear strategy to drive portfolio progression.

  • 2 Jahre und 5 Monate, Aug. 2014 - Dez. 2016

    Discovery Safety Group Leader in Pharmacokinetics Dynamics & Metabolism (PDM)

    Pfizer Inc.

    Lead scientific remit and strategic direction of the discovery toxicology discipline within PDM. Worked across the organization and lead matrix teams to develop and implemented novel in vitro safety assays and screening paradigms for prospective risk assessment.

  • 4 Jahre und 3 Monate, Juni 2010 - Aug. 2014

    Senior Principal Scientist

    Pfizer

    Head of in vitro models group and assay conduct group in Compound Safety Prediction with responsibility for developing a toxicology research program in early drug discovery. Focusing on understanding mechanisms of drug toxicity and developing and implementing prospective and predictive safety screens to identify safety liabilities early, to select the compound with the best safety profile for first in vivo toxicity assessment and to support project specific de-risking needs

  • 1 Jahr und 6 Monate, Dez. 2008 - Mai 2010

    Associate Director

    The Scripps Research Institute

    Rho-Kinase (Rock) inhibitor platform biology lead o Lead in vitro pharmacology efforts including assay development, HTS and hit to lead optimization Project manager for the Scripps Pfizer HTS assay development collaboration o Responsible for managing the joint collaboration, including the selection, prioritizing, staffing and development of HTS-ready assays.

  • 2 Jahre und 3 Monate, Okt. 2006 - Dez. 2008

    Senior Scientist

    The Scripps Research Institute

    Extension of previous role of staff scientist

  • 2 Jahre und 1 Monat, Sep. 2004 - Sep. 2006

    Staff Scientist

    The Scripps Research Institute

    Lead biologist in kinase oncology and inflammation projects. Responsible for the design, implementation, screening and analysis of biochemical and cell-based assays, including high-content screening (HCS), for high-throughput screening (HTS) campaigns and lead identification and optimization.

  • 3 Jahre und 6 Monate, März 2001 - Aug. 2004

    Research Associate

    The Scripps Research Institute

    Postdoctoral Research Associate in the group of Dr. Sandra Schmid. Worked on Receptor trafficking and signaling

Ausbildung von Thomas Schröter

  • 1997 - 2001

    Biochemistry

    Johann Wolfgang Goethe University

    Structure function relationship of trans membrane redox proteins

Sprachen

  • Englisch

    Fließend

  • Deutsch

    Muttersprache

  • Französisch

    Grundlagen

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