
Dr. Yan Wang-Walles
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Fähigkeiten und Kenntnisse
Werdegang
Berufserfahrung von Yan Wang-Walles
- Bis heute 15 Jahre und 7 Monate, seit Jan. 2010
R&D Professional
Basel
- Bis heute
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- 2007 - 2009
Research Investigator
National Institute of Health Baltimore US
Developed a new LC-MS assay to quantify acylcarnitine and CoA esters in tissue samples for study of cancer cachexia treatment. Investigated the pharmacokinetics and metabolism of (R,R)-4-methoxyfenoterol in human intestinal and liver microsomes by LC-MS/MS. Developed a CE method to determine the ATP/ADP levels in normal and irritated mitochondria to screen cell damage caused by exposure to high dose radiation. Developed a CE/LIF assay to determine free and protein bound glutathione in HepG2 cells.
- 2002 - 2006
Graduate Research Associate
University of Waterloo, Canada
Designed and Constructed laser desorption solid Phase microexctraction (SPME) interfaces to MS, GC/GC-MS and IMS. Lead industrial collaboration with MDS Sciex to design and develop automated SPME/MALDI MS device for peptides and protein digest analysis. Performed weekly tutorials mentored and evaluated student's performance.
- 1998 - 2000
Application Specialist
Nicolet Instrument Co. (now Thermo Fisher Scientific ) Beijing Office, China
Developed methods for FT-IR spectrometer applications in area of industrial quality control. Interacted with customers to demonstrate new FT-IR technology and applications Organized Nicolet FT-IR theory and application workshops.
- 1995 - 1998
Lecturer for Analytical Chemistry
University of Beijing, China
Instructed "analytical chemistry" and "chemical separation methods" courses. Conducted Laboratory demonstration for NMR spectrometer. Supervised undergraduate students for fourth year project.
Ausbildung von Yan Wang-Walles
- 2002 - 2006
Analytical Chemistry
University Of Waterloo, Canada
Laser Desorption and MALDI, Mass spectrometry, Ion mobility, sample preparation techniques
- 1992 - 1995
Organic Chemistry
Lanzhou University, China
Isolated and purified diterpenoid alkaloids from traditional Chinese herbal medicines and elucidated the structures using NMR.
Sprachen
Englisch
Fließend
Chinesisch
Muttersprache
Deutsch
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