Dipl.-Ing. Aksel de Vries

* Leading the integration of a diverse portfolio into the Digital Ecosystem, from plasma fractionation to formulation and packaging. * Conducted business benefits analyses to identify potential improvements and cost savings. Established a Due Diligence platform for decisions on roadmap, scope, CAPEX, OPEx. * Hosting SteerCo meetings with local and global senior leadership team (SLT). * Implementing effective Organizational Change Management strategies to ensure successful implementation of the MES roadmap

* Smart Manufacturing, beyond the hype. * 25 years of proficiency in MES / MOM / Quality Management across 5 continents. * Focus on MES excellence, as Portfolio Lead, Business Partner, Solution Architect, Technical Lead. * Delivered strategic Digital Maturity studies, Cost/Benefit business justifications, fit/gap assessments, facilitating digital transformation. * Demonstrated expertise as a Quality Assurance Officer, specializing in GAMP5, Critical Thinking, 21CFR11, Data Integrity, lifecycle management.

* Joined the QA-focused consultancy "PharmSupport" in the role of Associate Partner, to replace a retiring Partner, and to expand the company's portfolio with Manufacturing Execution Systems (MES). * Wrote a joint QA-MES business development plan. * Pioneered a comprehensive services portfolio, including a Digital Maturity template, MES Cost/Benefit and Fit/Gap methodology, Deployment strategy, etc. * Laid the strategic foundation for PharmSupport to triple their MES turnover and engineer's base.

* Successfully delivered a quantitative Business Case model to support strategic decision-making. * Co-developed an effective MES/CSV Recipe Validation Strategy, focusing on Data Integrity. * Provided strategic consultancy for the MES Center of Excellence, facilitating the harmonization of local IT teams into CORE Shared Services. * Demonstrated expertise in streamlining processes and optimizing technologies to capture value.

* Streamlined the MES roadmap for a CGT greenfield site, aligned with Global standards and local needs. * Revamped the Validation Plan to incorporate local functional scope and planning agile PAS|X demo's. * Established the benchmark for ADKAR Org. Change.

* Developed and executed a highly effective QA-strategy for MES in a volatile greenfield project, ensuring successful delivery on all promises. * Secured the MES production license for personalized vaccines, demonstrating meticulous attention to detail and compliance. * Undertook additional projects through HGP (now NNiT), providing expert MES-QA consultancy services for Torrent Pharma (India) and LifeScan / Johnson & Johnson (Scotland).

* Joined Zenith as MES engineer #2 ... progressed to MES Associate Director at Cognizant * Played a pivotal role in establishing Zenith's MES domain. * Case studies for Merck, Novartis, Wyeth/Pfizer, DSM, etc. * MES Tech Lead at GSK, oversaw 30 offshore engineers, three-tier 24/7 support for 28 sites, established a MES services portfolio. * Designed and executed a MES Disaster Recovery program for 80 GSK sites. * Demonstrated expertise as an MES business/sales consultant at Cognizant.

* Joined AspenTech as a PIMS engineer, delivering customer support and creating/delivering advanced MES training. * Expert MES technical consultancy for sales and pilot projects, in verticals such as chemistry, pharma, food & beverage, metals, pulp & paper, oil & gas. * Led a MES demo at the 2001 “Aspen World” fair, covering end-to-end ISA-88/95. * Seconded as the MES technical lead at Sanofi-Aventis for 3 years, managing the deployment of a 20 million MES project across Paris, Rouen, Frankfurt, London.

* Technical MBA, focusing on Digital Ecosystems, Corporate Strategy, Design Innovation 4.0, Corporate Finance & Business Benefits, Digital Business Process Mapping, Integrated Plant Management, Innovation Strategy & Systems, Advanced Project & Portfolio Management, High-Tech Marketing, IoT Service Design. * Thesis on Technology Battles and Format Wars between RAMI4.0 and ISA-88/95. * Explored a hundred models on corporate readiness for Industry4.0 ... in-depth study of Digital Maturity Models.

Graduated from Technical University Eindhoven on optimization of a trickle-bed by inducing pulsing flow.

Graduated from Technical University Eindhoven on optimization of a trickle-bed with pulsing flow.