Dr. Meltem Barlin

• Established the role of NOX4 in regulation of cancer cell transformation via sustaining actin filament polymerization, to promote YAP1 nuclear localization, as well as BRD4 expression serving as effectors that selectively promote transcriptional addiction to support NSCLC survival. • Determine GSTP1 silencing in breast cancer as a redox vulnerability that redirects the flux of cysteine oxidation in the proteome

Department for Dermatology & Venereology Developing the Doctoral thesis in association with the Graduate School for Biological Science (Cologne) • Demonstrate that XIAPS is involved in melanoma cell migration and invasion through vimentin and focal adhesion formation. • Identified a novel anti-apoptotic function of XIAP to contribute to target XIAP in tumor growth and metastasis

• Proved that Gar22β is a novel regulator of cell adhesion and migration and provide a foundation for understanding the molecular basis of diverse cytoskeleton-dependent processes

Genotyping of mice tail cuts

Research internship . Participation in experimental testing of a newly developed thermal cycler; ‚Implementation and optimization of a PCR assay; Quantitative fluorescence measurements of hybridization probes modified with rare earth elements; strain maintenance of bacteria; cultivation of various microorganisms

Internship and developing of the Bachelor´s thesis

Internship during my studies for the bachelor of science at the Hochschule Niederrhein: workup and assessment of tissue samples from all parts of the body; Immunohistochemical staining

Weiße Biotechnologie, Rote Biotechnologie

Instrumentelle Analytik, Gentechnik, Mikrobiologie