Amin Shadfar

Research on Cell Fate Determination and Cellular Reprogramming (PhD). Applied molecular imaging techniques to visualise cell fate in live organisms and utilised statistical tools to analyse large data sets. Targeted metabolic pathways to advance regenerative medicine applications, potentially leading to increased efficiency in cell therapy. Generated transgenic animals (CRISPR) and mapped critical cellular nutrient transporters and signalling components influencing metabolism and reproductive function.

Thesis focused on identification of molecular barriers to direct cellular reprogramming in model organisms and improving the quality and efficiency of cell therapies.

Characterised receptor responses using fluorescent imaging (Olympus) to quantify drug efficacy (Excel, Sigma Plot) validating target engagement for diseases of the eye.

Utilised engineered colorectal cancer cell lines to determine the chemotherapeutic potential of the drug candidate Entinostat.

Executed key laboratory protocols for varicose vein research. Standardised surgical patient samples, ensuring data integrity required for the ongoing clinical study.

English language tutor for adult students at beginner and intermediate levels.

Interpreter for asylum seekers: psychological counselling and medical services. Cross-cultural communication, negotiation and handling sensitive information.