Melinda Fekete

• Designing, screening and optimizing synthesis routes for chemical as well as biocatalytic processes • Identification, qualitative and quantitative analysis of target molecules and side products • Scaling the optimized processes from mL to several L-scale • Downstream, isolation and purification of target compound • Writing project reports and proposals • Downstream, isolation and purification of target compound

Identification and isolation of autoantibodies from human serum that are related to Dilated Cardiomyiopathy.

• Process development and reaction optimization for customers; • Transferring chemical reactions into flow processes such as high temperature - high pressure reactions, exothermic reactions, ionic liquid synthesis and hydrogenations. • Catalyst screening for fixed-bed reactors; • Writing project reports, application notes and publications; • Demonstrations on conferences and customers’ sites.

DNA-binding and self-association of the human recombinase protein Rad51.

• Catalysis and process development; • Olefin oligomerization in batch and fixed-bed reactors; • Supported Ionic Liquid Phase catalysis; • Synthesis of high purity ionic liquids and air-sensitive organometallic catalysts; • Studies on ionic liquids and liquid crystalline structures: viscosity, DSC, POM.

Synthesis of novel ionic liquids for different applications.

Synthesis of pharmacologically active compounds;

Synthesis of novel biologically active heterocycles via Palladium-catalyzed cross-couplings.

Specialization: Organic Chemistry and Pharmaceutical Processes. Diploma Thesis: One-pot transformation of cyclic phosphine-oxides to phosphine-boranes by dimethylsulfide-borane.