Rainer Wolber

• Research & Development • Medical & Clinical Science • Strategic Innovation & Project Management R&D • Regulatory Affairs & Chemical Compliance

• clinical strategy & documentation for Dräger products – Medical Division • health economics

• technological and clinical strategy Hansaplast / Elastoplast / ABC / Guttaplast • Medical Device Regulation (MDR) implementation board

• founding member of business unit ‘Health Care’ • strategy development (research and development incl. packaging development, medical & clinical affairs as well as regulatory affairs for all ‘Health Care’ products (Hansaplast / Elastoplast / ABC / Guttaplast), incl. postmarket surveillance • intermediary to competent authorities, notified bodies and external cooperation partners

• pipeline and product portfolio responsibility ‘Hansaplast/Elastoplast’ (medical devices, pharmaceuticals, cosmetics, biocides, personal protection equipment (PPE) • technology and patent strategy

• pipeline and product portfolio responsibility Eucerin (dermo cosmetics with diverse technologies: emulsions, surfactant systems, aerosols, UV filters, active ingredients) • intermediary to international marketing and medical management Eucerin as well as academia / KOLs and external cooperation partners

• pipeline and product portfolio responsibility ‘Hansaplast/Elstoplast’ (medical devices, pharmaceuticals, cosmetics, biocides, personal protection equipment (PPE) • steering cooperation with universities, scientific institutions, key opinion leaders (KOLs) and industrial partners • steering of clinical trials, complex volunteer studies and in vitro examinations, mainly for medical devices and cosmetics

• research of skin pigmentation physiology and skin interaction with topical sun care products (focus: skin pigmentation) • steering international research cooperation (diverse universities, NIH (Bethesda, USA), DKFZ) • member of COLIPA Task Force ‘In vitro Protection Methods - Sun Care’, Brussels, Belgium • assay development for in vivo, ex vivo and in vitro studies (focus: own organotypical 3D skin models) • in silico assay development

• research on physiology of skin´s own protection mechanism and its interaction with topical sun care products (focus: antiinflammatory systems, antioxidants) • screening assay development (in vitro / primary cell cultures) incl. high-throughput screening (HTS) • development of non-invasive biophysical methods for efficacy proof topically applied products

• researching healthy and damaged skin physiology using in vitro / ex vivo and in vivo methods (biochemical / cell biological / biophysical) • executing volunteer studies (in vivo) with non-invasive, biophysical techniques for efficacy proof of (dermo-) cosmetic products

• researching the interaction of microorganisms (permanent skin flora and pathogenic germs) with human skin as well as the necessary assay development (in vitro / ex vivo / in vivo) • identification of active ingredients to influence skin´s microflora

• Thema der Dissertation: „Einfluss von oxidativem Stress auf die menschliche Haut unter besonderer Berücksichtigung des Atopischen Ekzems“ • Schwerpunkte: Biochemie / Molekularbiologie / Zellbiologie

• Thema der Diplomarbeit „Endogene Schutzmechanismen der Haut gegen UV-Strahlung“ • Schwerpunkte: Biochemie / Molekularbiologie / Zellbiologie