Dr. Gérard Leboulle

Design and development of real-time PCR assay (TaqMan probes, SimpleProbe, Hybridisation probes, molecular beacons) for nucleic acid quantification and typing, in single detection and multiplex formats. Customer support: Assay design, information on our portfolio (research use only and CE in vitro diagnostic kits), sales and support by troubleshooting. Participation to the certification of CE IVD kits.

Design of real-time PCR assay (TaqMan probes, SimpleProbe)

I analyse the molecular mechanisms of learning and memory in the honeybee Apis mellifera and perform neuroanatomical studies. I develop and apply molecular techniques to modulate the physiology of the brain. I finance my own research, am active in project management (planning of experiments and work at the bench) and laboratory organisation. I document and communicate my results. I develop new collaborations and a research unit.

Managing of ongoing projects.

I was involved in a joint project on hygienic behaviour that might be economically relevant. Studies on the glutamatergic neurotransmission and on the development of molecular tools to modulate brain physiology were continued. I financed my own research, was involved in project management and laboratory organisation. I managed several projects at the same time and led a research group of up to 4 members. I documented and communicated my results and was involved in teaching and in several collaborations.

Managing of ongoing projects.

I initiated a study on the glutamatergic neurotransmission of the honeybee. I contributed to the annotation process of the genome. I worked on the development of molecular tools to modify gene expression in the brain. I financed my own research, was involved in project management and laboratory organisation. I managed several projects at the same time and led a research group of up to 6 members. I documented and communicated my results and was involved in teaching and in several collaborations.

I studied the modality of cAMP dependent protein kinase (PKA) activation. The development of molecular tools to modulate brain physiology was undertaken.

Specialisation in Immunobiology and Parasitology. I characterized Ixodes ricinus tick factors that modulate the host’s defences and that could enable the transmission of pathogens. The laboratory had contacts with pharmaceutical industries and applied GLP and GMP guidances.

M.S. in Zoological Sciences with Honours. Master thesis in Immunology. I identified genes whose expression is induced in T lymphocytes by an analogue of the cortisol hormone in relation to its role on apoptosis.