Markus Fries

In charge of directing and managing regulatory affairs activities for developing global strategies across product life cycles with a focus on CMC. Lead the preparation and filing of CMC sections of regulatory submissions and interactions with regulatory agencies. Develop global CMC regulatory strategy for investigational and marketed products. Manage regulatory assessment and guidance on product compliance topics.

Development of new therapies for the treatment of haemophilia.

Elucidating mechanism and specificity of the virulence factors pectin methylesterase and pectate lyase. Supervision of PhD, masters and bachelor students as well as a lab technican.

Crystallographic studies of the thrombin-inhibitor heparin cofactor II

Protein-protein interaction and catalysis in the pyruvate dehydrogenase multienzyme complex

Diplom thesis: Expression, purification and crystallisation of the membrane protein dihydroorotate dehydrogenase Diplom subjects: Biochemistry, Molecular Biology, Immunology; Vordiplom subjects: Physics, Chemistry, Biology, Biochemistry, Physiology, Cell Biology, Anatomy and Histology